Watch Demi Moore, Margaret Qualley and Dennis Quaid in the trailer for The Substance

MUBI, the global film distributor, production company and streaming service has released the brand-new full-length trailer for Coralie Fargeat’s (Revenge) deliriously entertaining and ruthlessly satirical new film The Substance, starring Demi Moore, Margaret Qualley and Dennis Quaid. The Substance received its World Premiere at the 77th Cannes Film Festival to riotous acclaim, winning the prize for Best Screenplay, and will be released in cinemas in the UK and Ireland on 20 September 2024.

Have you ever dreamt of a better version of yourself?

You. Only better in every way. 

You’ve got to try this product: The Substance.

It changed my life.

Demi Moore gives a career-best performance as Elisabeth Sparkle, a former A-lister past her prime and suddenly fired from her fitness TV show by repellent studio head Harvey (Dennis Quaid).

She is then drawn to the opportunity presented by a mysterious new drug: THE SUBSTANCE. All it takes is one injection and she is reborn – temporarily – as the gorgeous, twenty-something Sue (Margaret Qualley).

The only rule? Time needs to be split: exactly one week in one body, then one week in the other. No exceptions. A perfect balance. What could go wrong?

Coralie Fargeat’s Cannes sensation turns toxic beauty culture inside out with a be-careful-what-you-wish-for fable for the ages. Explosive, provocative and twisted, The Substance marks the arrival of a thrillingly visionary filmmaker.